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George I Papakostas Selected Research

Fluoxetine (Prozac)

6/2012Prevalence of MTHFR C677T and MS A2756G polymorphisms in major depressive disorder, and their impact on response to fluoxetine treatment.
4/2011Efficacy of antidepressants for dysthymia: a meta-analysis of placebo-controlled randomized trials.
7/2010Anxious depression and early changes in the HAMD-17 anxiety-somatization factor items and antidepressant treatment outcome.
3/2010Type of residual symptom and risk of relapse during the continuation/maintenance phase treatment of major depressive disorder with the selective serotonin reuptake inhibitor fluoxetine.
2/2010Residual sleep disturbance and risk of relapse during the continuation/maintenance phase treatment of major depressive disorder with the selective serotonin reuptake inhibitor fluoxetine.
10/2008Psychic and somatic anxiety symptoms as predictors of response to fluoxetine in major depressive disorder.
2/2007Extreme response style in recurrent and chronically depressed patients: change with antidepressant administration and stability during continuation treatment.
1/2007Hopelessness as a predictor of non-response to fluoxetine in major depressive disorder.
7/2006Somatic symptoms in outpatients with major depressive disorder treated with fluoxetine.
6/2006Serum prolactin levels among outpatients with major depressive disorder during the acute phase of treatment with fluoxetine.
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George I Papakostas Research Topics

Disease

134Major Depressive Disorder (Major Depressive Disorders)
01/2022 - 07/2002
25Treatment-Resistant Depressive Disorder
01/2021 - 01/2003
6Mood Disorders (Mood Disorder)
01/2021 - 02/2004
6Fatigue
10/2020 - 01/2006
5Sleepiness
12/2020 - 01/2006
5Sleep Initiation and Maintenance Disorders (Insomnia)
12/2020 - 06/2006
5Nausea
01/2019 - 06/2006
5Medically Unexplained Symptoms
07/2007 - 05/2003
4Bipolar Disorder (Manic Depressive Psychosis)
05/2016 - 12/2004
4Hypercholesterolemia
03/2004 - 07/2002
3Panic Disorder (Panic Attack)
01/2021 - 11/2019
3Obesity
05/2020 - 11/2015
3Headache (Headaches)
01/2019 - 10/2006
3Neurobehavioral Manifestations
01/2018 - 11/2006
3Cognitive Dysfunction
10/2015 - 02/2012
3Dysthymic Disorder
10/2011 - 04/2011
2Depressive Disorder (Melancholia)
01/2021 - 11/2019
2Weight Gain
01/2017 - 01/2008
2Hyperprolactinemia
06/2006 - 12/2004
2Personality Disorders (Personality Disorder)
11/2003 - 09/2002
1Overweight
05/2020
1Dyskinesias (Dyskinesia)
01/2017
1Psychomotor Agitation (Akathisia)
01/2017
1Pain (Aches)
12/2015
1Inflammation (Inflammations)
08/2014

Drug/Important Bio-Agent (IBA)

74Antidepressive Agents (Antidepressants)IBA
01/2022 - 09/2002
29Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2018 - 03/2003
24Fluoxetine (Prozac)FDA LinkGeneric
06/2012 - 07/2002
10EscitalopramFDA Link
01/2018 - 06/2009
10Antipsychotic Agents (Antipsychotics)IBA
01/2018 - 02/2004
10Bupropion (Wellbutrin)FDA LinkGeneric
02/2014 - 03/2003
9KetamineFDA LinkGeneric
01/2021 - 01/2019
9Norepinephrine (Noradrenaline)FDA LinkGeneric
02/2014 - 12/2006
8HomocysteineIBA
02/2021 - 08/2004
7Pharmaceutical PreparationsIBA
05/2016 - 02/2006
7Nortriptyline (Aventyl)FDA LinkGeneric
04/2011 - 01/2003
6Folic Acid (Vitamin M)FDA LinkGeneric
02/2021 - 08/2004
6Biomarkers (Surrogate Marker)IBA
01/2021 - 03/2004
6ziprasidone (Geodon)FDA Link
01/2018 - 02/2004
6CholesterolIBA
12/2005 - 07/2002
5S-Adenosylmethionine (Ademetionine)IBA
02/2021 - 01/2009
55-methyltetrahydrofolateIBA
05/2016 - 06/2012
5Sertraline (Zoloft)FDA LinkGeneric
02/2014 - 09/2003
5Serotonin (5 Hydroxytryptamine)IBA
01/2014 - 01/2007
5Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
12/2005 - 08/2004
4Dopamine (Intropin)FDA LinkGeneric
02/2014 - 12/2006
3VortioxetineIBA
01/2021 - 12/2014
3EsketamineIBA
01/2021 - 01/2020
3pimavanserinIBA
12/2020 - 01/2019
3Testosterone (Sustanon)FDA Link
10/2020 - 12/2004
3Quetiapine Fumarate (Seroquel)FDA Link
01/2014 - 05/2013
3Methionine (L-Methionine)FDA Link
06/2012 - 08/2010
3nefazodone (Serzone)FDA LinkGeneric
08/2011 - 10/2007
3Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric
04/2011 - 11/2006
3Duloxetine Hydrochloride (Cymbalta)FDA Link
04/2011 - 01/2006
3ProlactinIBA
06/2006 - 05/2003
3LithiumIBA
12/2004 - 02/2003
2agomelatine (S20098)IBA
01/2018 - 04/2011
2tianeptine (Stablon)IBA
10/2015 - 04/2011
2Paroxetine (Paxil)FDA LinkGeneric
02/2014 - 04/2011
2Serotonin and Noradrenaline Reuptake InhibitorsIBA
01/2014 - 06/2009
2Desvenlafaxine SuccinateFDA Link
11/2013 - 04/2011
2Aripiprazole (Abilify)FDA Link
03/2012 - 10/2005
2CitalopramFDA LinkGeneric
04/2011 - 11/2006
2Trazodone (Trittico)FDA LinkGeneric
04/2011 - 10/2007
2Milnacipran (Ixel)FDA Link
04/2011 - 01/2007
2Reboxetine (Vestra)IBA
04/2011 - 02/2008
2Desipramine (Pertofrane)FDA LinkGeneric
04/2011 - 08/2004
2Moclobemide (Arima)IBA
04/2011 - 10/2006
2Hydrocortisone (Cortisol)FDA LinkGeneric
03/2010 - 05/2003
2Triiodothyronine (Liothyronine)FDA LinkGeneric
01/2009 - 08/2005
1Inositol (Myoinositol)IBA
02/2021
1coenzyme Q10 (CoQ10)IBA
02/2021
1Acetylcarnitine (Alcar)IBA
02/2021
1Acetylcysteine (Siran)FDA LinkGeneric
02/2021
1Thioctic Acid (Lipoic Acid)IBA
02/2021
1MagnesiumIBA
02/2021
1Tryptophan (L-Tryptophan)FDA Link
02/2021
1Vitamin DFDA LinkGeneric
02/2021
1ZincIBA
02/2021
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
02/2021
1N-Methylaspartate (NMDA)IBA
01/2020
1AticaprantIBA
01/2020
1NSI-189IBA
01/2020
1Narcotic Antagonists (Opioid Antagonists)IBA
01/2020
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2020
1Brain-Derived Neurotrophic Factor (BDNF)IBA
12/2019
1LeptinIBA
12/2019
1Midazolam (Versed)FDA LinkGeneric
01/2019
1PlacebosIBA
01/2018
1CalciumIBA
12/2015
1Interleukin-2 (IL2)IBA
11/2015
1Interleukin-6 (Interleukin 6)IBA
11/2015
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
10/2015
1Histamine (Histamine Dihydrochloride)FDA Link
08/2014
1Carnitine (L-Carnitine)FDA LinkGeneric
08/2014
1Neurotransmitter Agents (Neurotransmitter)IBA
02/2012
12-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA
10/2011

Therapy/Procedure

17Therapeutics
01/2020 - 09/2004
7Drug Therapy (Chemotherapy)
01/2020 - 08/2004